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    SynSmart offers a vast range of synthetic chemistry services through an experienced scientific team with the aim of accelerating diverse synthetic and drug discovery needs of innovator biotech and pharmaceutical companies across the globe. With our skills of tackling complex synthetic routes with different approaches, we endeavor for synthesizing high quality compounds at rapid speed. SynSmart works  on early-stage discovery projects for pharma/ biotech customers in making intermediates, building blocks and final compounds from mg to multi-g scale. 

    SynSmart offers chemistry services under flexible business arrangements including Fee for Service (FFS), Time & Material based arrangement or Full-Time Equivalent (FTE) based.

    Our expertise in synthetic chemistry

    Traditional Heterocyclic Chemistry

    Synthesis of O, N, S and P heterocyclic and fused-ring analogues, Benzofuran formation, Azaindole Chemistry, Thiophene ring formation, Thiazole formation etc.

    Transition Metal-mediated Reactions

    Suzuki coupling, Negishi & Heck Coupling, Buchwald-Hartwig Coupling, Phosphonate Chemistry, C-P, C-S, C-B, C-Sn and C-Si bond forming reactions, C-H activations etc.

    Difficult-to-handle and Sensitive Reagents

    Including all kinds of metal-based pyrophoric reagents like lithium, magnesium and zincs, toxic reagents like metallic cyanides and metal carbonyls e.g., Reduction, Catalytic hydrogenation, Grignard, Hydroxymethylation etc.

    Handling of Gaseous Reagents

    Experienced in reactions involving gases like H2, Cl2 , O2 , CO, CO2, SO3 etc. – in addition to rarer reactions like ozonolysis – even at larger scales. e.g. Chloromethylation, Bromination & Selective Reduction, all types of Halogenation

    High-temperature reactions at 290 °C

    Nitration, Reduction and Migration

    Special Synthetic reactions

    Cryogenic Reactions, Use of pyrophoric reagents, fluorinations, synthesis of fluoroalkyl and fluoro alkoxy targets, cyclopropanations, deuterations, labeling and isotope synthesis and much more.

    Our chemical synthesis capabilities

    Where can I go to provide a sample for testing?

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    What happens to my sample once I have provided it?

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    What will laboratory testing cost me?

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